Technology
GPB Microchip at 300 Micron Scale
For a detailed description of the technology, please review the articles listed on the Publications page. In summary, the technology uses a microchip design with an array of posts, designed to establish a laminar flow that deflects large cells in one direction while small cells and serum follow a randomized path. Cells are sorted continuously according to size as they gently flow through the array. Depending on the configuration and spacing of the posts, cells above a certain threshold size will always be deflected in a predetermined direction, resulting in the quantitative recovery of leukocytes.
Huang et al., Science 304, 987 (2004)