Publications
The following papers describe a few of the applications as well as experimental and clinical results of the GPB technology:
Size-based selection
- Continuous particle separation through deterministic lateral displacement [Science 2004; 304:987-990]
- Deterministic hydrodynamics: Taking blood apart [Proc Nat Acad Sci 2008; 103:14779-14784]
- A microfluidics approach for the isolation of nucleated red blood cells (NRBCs) from the peripheral blood of pregnant women [Prenat Diagn 2008; 28:892-899]
- Crossing microfluidic streamlines to lyse, label and wash cells [Lab Chip 2008; 8:1448-53]
Affinity-capture
- Isolation of rare circulating tumour cells in cancer patients by microchip technology [Nature 2007; 450:1235-1239]
- Detection of mutations in EGFR in circulating lung-cancer cells [N Engl J Med 2008; 359:366-77]